It has been well established in the last year that the "good" acne products can make skin look flabby. There is no longer any dispute that these products work and that the "bad" ones can lead to a skin condition called "pigmentation." The problem is that there is no one product that is completely free from pigmentation. To get a clearer understanding of what is going on in the skin when people have "pigmentation" we can turn to the skin biopsy of a person with "pigmentation" in their skin. The biopsy is done using a needle and a small sample of a person's skin. The sample is then tested for any pigmentation and for the presence of pigmentation-causing substances. For this photo I have a photo taken from a person's eye. Here is a photo taken with a microscope showing what the cells look like in a person's skin. A few of these cells are red and it looks like the person has red eye pigment (from a childhood condition called erythema multiforme or erythema nodosa ). The pigmentation is from an oil-based pigment called dermestane. The pigmentation from this oil-based pigment is not very visible, but is a source of irritation and sensitivity.